O LECT investiga os efeitos de contaminantes emergentes na fisiologia de mamíferos, com foco em alterações morfofisiológicas e na modulação da expressão gênica nos seus diferentes sistemas orgânicos. As pesquisas abrangem disfunções metabólicas e reprodutivas causadas por misturas de contaminantes no Espírito Santo, e os efeitos da co-exposição pré-natal ao tributilestanho e a dietas ricas em carboidratos refinados na saúde de mães e filhotes.
Pesquisador do INCT:
Prof. Dr. Jones Bernardes Graceli/ PQ-1D
Lattes
Laboratório de Endocrinologia e Toxicologia Celular, Departamento de Morfologia/CCS, Universidade Federal do Espírito Santo
Av. Marechal Campos, 1468, Prédio do básico I, sala 5, 290440-090 Vitória, ES, Brazil
Tel.: +55-27-33357540/ 7369; Fax: +55-27-33357358
E-mail: jbgraceli@gmail.com
Site: LETC
Animal Science, School of Agricultural Sciences (SOAS)
College of Agricultural, Life, and Physical Sciences
Southern Illinois University Carbondale, 1205 Lincoln Drive, MC 4417, Carbondale, IL 62901, USA. Tel: (618)453-6537 (Office), Tel: (618)453.2329 (Office of SOAS)
E-mail: jbgraceli@siu.edu
Site
Financiamentos vigentes:
2025-2026-Project Proposal Submitted for Funding by the SIU FOUNDATION AND VICE CHANCELLOR OF RESEARCH: CHRONIC EXPOSURE TO A MIXTURE OF PHTHALATES AND TOXICITY IN FEMALE ADIPOSE TISSUES.
Budget request: $13,750.00
2025-2027-Project Proposal Submitted for Funding by the Grayson-Jockey Club Research Foundation Proposal Title: A Molecular Study on Hemorrhagic Anovulatory Follicles (#1081). Budget request: $70,724.00 Grayson-Jockey Club Research Foundation.
2023-2025 “Metabolic and reproductive disorders caused by exposure to emerging contaminant mixtures in Espírito Santo, Brazil.” approved by CNPq/FAPES 19/2022 (#981/2022). Direct Costs: Direct Costs: ~ $ 140,000
2022-2026: Co-exposure to obesogen tributyltin and high carbohydrate diet leading to metabolic and reproductive complications submitted by CNPq 04/2021 (PQ). Direct Costs: Direct Costs: ~ $ 10,200.